As filed with the Securities and Exchange Commission on March 13, 2024

Registration No. 333-

 

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549 

 

 

FORM S-8

REGISTRATION STATEMENT

UNDER

THE SECURITIES ACT OF 1933

 

 

ENTRADA THERAPEUTICS, INC.

(Exact name of registrant as specified in its charter) 

 

 

Delaware   81-3983399

(State or other jurisdiction of

incorporation or organization)

 

(I.R.S. Employer

Identification No.)

   

One Design Center Place

Suite 17-500

Boston, MA

  02210
(Address of Principal Executive Offices)   (Zip Code)

 

Entrada Therapeutics, Inc. 2021 Stock Option and Incentive Plan

Entrada Therapeutics, Inc. 2021 Employee Stock Purchase Plan

(Full title of the plans)

 

Dipal Doshi

Chief Executive Officer

Entrada Therapeutics, Inc.

One Design Center Place

Suite 17-500

Boston, MA 02210

(Name and address of agent for service)

 

(857) 520-9158

(Telephone number, including area code, of agent for service)

 

 

Copies to:

 

Kingsley L. Taft

Sarah Ashfaq

Goodwin Procter LLP

100 Northern Avenue

Boston, Massachusetts 02210

(617) 570-1000

 

 

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

 

Large accelerated filer ¨   Accelerated filer ¨
       
Non-accelerated filer x   Smaller reporting company x
       
      Emerging growth company x

 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ¨

 

 

 

 

 

 

EXPLANATORY NOTE

 

This Registration Statement on Form S-8 (this “Registration Statement”) is filed for the purposes of registering (i) an additional 1,338,081 shares of common stock, par value $0.0001 per share (the “common stock”), of Entrada Therapeutics, Inc. (the “Registrant”) that may be issued pursuant to the Entrada Therapeutics, Inc. 2021 Stock Option and Incentive Plan (the “2021 Plan”) and (ii) an additional 334,520 shares of common stock that may be issued pursuant to the Entrada Therapeutics, Inc. 2021 Employee Stock Purchase Plan (the “2021 ESPP”). The number of shares of common stock reserved and available for issuance under the 2021 Plan is subject to an automatic annual increase on each January 1 by an amount equal to the lesser of: (i) four percent (4%) of the number of shares of common stock issued and outstanding on the immediately preceding December 31, or (ii) such number of shares of common stock as determined by the Administrator (as defined in the 2021 Plan). Accordingly, on January 1, 2024, the number of shares of common stock reserved and available for issuance under the 2021 Plan increased by 1,338,081. This Registration Statement registers these additional 1,338,081 shares of common stock. The additional shares are of the same class as other securities relating to the 2021 Plan for which the Registrant’s registration statements filed on Form S-8 (File No. 333-260563, File No. 333-263556 and File No. 333-270286) filed with the Securities and Exchange Commission (the “SEC”) on October 28, 2021, March 15, 2022 and March 6, 2023, respectively, are effective. The number of shares of common stock reserved and available for issuance under the 2021 ESPP is subject to an automatic annual increase on each January 1 by an amount equal to the lesser of: (i) 557,524 shares of common stock, (ii) one percent (1%) of the number of shares of common stock issued and outstanding on the immediately preceding December 31, or (iii) such number of shares of common stock as determined by the Administrator (as defined in the 2021 ESPP). Accordingly, on January 1, 2024, the number of shares of common stock reserved and available for issuance under the 2021 ESPP increased by 334,520. This Registration Statement registers these additional 334,520 shares of common stock. The additional shares are of the same class as other securities relating to the 2021 ESPP for which the Registrant’s registration statements filed on Form S-8 (File No. 333-260563, File No. 333-263556 and File No. 333-270286) filed with the SEC on October 28, 2021, March 15, 2022 and March 6, 2023, respectively, are effective. The information contained in the Registrant’s registration statements on Form S-8 (File No. 333-260563, File No. 333-263556 and File No. 333-270286) is hereby incorporated by reference pursuant to General Instruction E, except for “Item 8. Exhibits.”

 

 

 

 

PART II

 

INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

 

Item 8. Exhibits.

 

See the Exhibit Index for a list of exhibits filed as part of this Registration Statement, which Exhibit Index is incorporated herein by reference.

 

EXHIBIT INDEX

 

Exhibit
No.
  Description
4.1   Fourth Amended and Restated Certificate of Incorporation of the Registrant (incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K (File No. 001-40969) filed by the Registrant on November 2, 2021).
   
4.2   Amended and Restated Bylaws of the Registrant (incorporated by reference to Exhibit 3.2 to the Registrant’s Current Report on Form 8-K (File No. 001-40969) filed by the Registrant on November 2, 2021).
   
4.3   Amended and Restated Investors’ Rights Agreement among the Registrant and certain of its stockholders, dated as of March 29, 2021 (incorporated by reference to Exhibit 4.2 to the Registrant’s Registration Statement on Form S-1 (File No. 333-260160), filed by the Registrant on October 8, 2021).
   
5.1*   Opinion of Goodwin Procter LLP.
   
23.1*   Consent of Ernst & Young LLP, independent registered public accounting firm.
   
23.2*   Consent of Goodwin Procter LLP (included in Exhibit 5.1).
   
24.1*   Power of Attorney (included on signature page).
   
99.1   2016 Stock Incentive Plan, and forms of award agreements thereunder (incorporated by reference to Exhibit 10.1 to the Registrant’s Registration Statement on Form S-1, as amended (File No. 333-260160), filed by the Registrant on October 25, 2021).
   
99.2   2021 Stock Option and Incentive Plan, and forms of award agreements thereunder (incorporated by reference to Exhibit 10.2 to the Registrant’s Registration Statement on Form S-1, as amended (File No. 333-260160), filed by the Registrant on October 25, 2021).
   
99.3   2021 Employee Stock Purchase Plan (incorporated by reference to Exhibit 10.3 to the Registrant’s Registration Statement on Form S-1, as amended (File No. 333-260160), filed by the Registrant on October 25, 2021).
   
107*   Filing Fee Table.

 

*   Filed herewith.

 

 

 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Act of 1933, as amended, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Boston, Commonwealth of Massachusetts, on this 13th day of March, 2024.

 

  ENTRADA THERAPEUTICS, INC.
     
  By: /s/ Dipal Doshi
  Name: Dipal Doshi
  Title: Chief Executive Officer (Principal Executive Officer)

 

POWER OF ATTORNEY AND SIGNATURES

 

KNOW ALL BY THESE PRESENT, that each individual whose signature appears below hereby constitutes and appoints each of Dipal Doshi and Kory Wentworth as such person’s true and lawful attorney-in-fact and agent with full power of substitution and resubstitution, for such person in such person’s name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration Statement on Form S-8, and to file the same, with all exhibits thereto, and all documents in connection therewith, with the Securities and Exchange Commission granting unto each said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as such person might or could do in person, hereby ratifying and confirming all that any said attorney-in-fact and agent, or any substitute or substitutes of any of them, may lawfully do or cause to be done by virtue hereof.

 

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in their capacities and on the date indicated below.

 

Name   Title   Date
/s/ Dipal Doshi   Chief Executive Officer and Director   March 13, 2024
Dipal Doshi   (Principal Executive Officer)    
         
/s/ Kory Wentworth   Chief Financial Officer   March 13, 2024
Kory Wentworth   (Principal Financial and Accounting Officer)    
         
/s/ Kush M. Parmar, M.D., Ph.D.   Chairman and Director   March 13, 2024
Kush M. Parmar, M.D., Ph.D.        
         
/s/ Gina Chapman   Director   March 13, 2024
Gina Chapman        
         
/s/ Peter S. Kim, Ph.D.   Director   March 13, 2024
Peter S. Kim, Ph.D.        
         
/s/ Mary Thistle   Director   March 13, 2024
Mary Thistle        
         
/s/ Bernhardt Zeiher, M.D.   Director   March 13, 2024
Bernhardt Zeiher, M.D.        

 

 

 

 

Exhibit 5.1

 

 

Goodwin Procter LLP

100 Northern Avenue

Boston, Massachusetts 02210

 

March 13, 2024

 

Entrada Therapeutics, Inc.

One Design Center Place

Suite 17-500

Boston, MA 02210

 

Re:         Securities Being Registered under Registration Statement on Form S-8

 

We have acted as counsel to you in connection with your filing of a Registration Statement on Form S-8 (the “Registration Statement”) pursuant to the Securities Act of 1933, as amended (the “Securities Act”), on or about the date hereof relating to an aggregate of 1,672,601 shares (the “Shares”) of common stock, $0.0001 par value per share (“Common Stock”), of Entrada Therapeutics, Inc., a Delaware corporation (the “Company”), that may be issued pursuant to the Company’s 2021 Stock Option and Incentive Plan and 2021 Employee Stock Purchase Plan (collectively, the “Plans”).

 

We have reviewed such documents and made such examination of law as we have deemed appropriate to give the opinion set forth below. We have relied, without independent verification, on certificates of public officials and, as to matters of fact material to the opinion set forth below, on certificates of officers of the Company.

 

The opinion set forth below is limited to the Delaware General Corporation Law.

 

For purposes of the opinion set forth below, we have assumed that no event occurs that causes the number of authorized shares of Common Stock available for issuance by the Company to be less than the number of then unissued Shares.

 

Based on the foregoing, we are of the opinion that the Shares have been duly authorized and, upon issuance and delivery against payment therefor in accordance with the terms of the Plans, will be validly issued, fully paid and nonassessable.

 

This opinion letter and the opinion it contains shall be interpreted in accordance with the Core Opinion Principles as published in 74 Business Lawyer 815 (Summer 2019).

 

We hereby consent to the inclusion of this opinion as Exhibit 5.1 to the Registration Statement. In giving our consent, we do not admit that we are in the category of persons whose consent is required under Section 7 of the Securities Act or the rules and regulations thereunder.

 

  Very truly yours,
   
  /s/ Goodwin Procter LLP
  GOODWIN PROCTER LLP

 

 

 

 

Exhibit 23.1

 

Consent of Independent Registered Public Accounting Firm

 

We consent to the incorporation by reference in the Registration Statement (Form S-8) pertaining to the 2021 Stock Option and Incentive Plan and the 2021 Employee Stock Purchase Plan of Entrada Therapeutics, Inc. of our report dated March 13, 2024, with respect to the consolidated financial statements of Entrada Therapeutics, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2023, filed with the Securities and Exchange Commission.

 

/s/ Ernst & Young LLP
   
Boston, Massachusetts  
March 13, 2024  

 

 

 

 

Exhibit 107

 

Calculation of Filing Fee Tables

 

Form S-8

(Form Type)

 

Entrada Therapeutics, Inc.

(Exact Name of Registrant as Specified in its Charter)

 

Table 1: Newly Registered Securities

 

Security
Type
Security Class Title Fee
Calculation
Rule
Amount
Registered
(1)
Proposed
Maximum
Offering
Price Per
Share
Maximum
Aggregate
Offering Price
Fee Rate Amount of Registration
Fee
Equity 2021 Stock Option and Incentive Plan Common Stock, $0.0001 par value per share Rule 457(c) and Rule 457(h)(1) 1,338,081 (2) $12.39 (3) $16,578,823.59 $0.00014760 $2,447.04
Equity 2021 Employee Stock Purchase Plan Common Stock, $0.0001 par value per share Rule 457(c) and Rule 457(h)(1) 334,520 (4) $10.54 (5) $3,525,840.80 $0.00014760 $520.42
Total Offering Amounts   $20,104,664.39 $0.00014760 $2,967.46
Total Fee Offsets       N/A
Net Fee Due       $2,967.46

 

(1) Pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), this Registration Statement on Form S-8 (this “Registration Statement”) shall also cover any additional shares of common stock, $0.0001 par value per share (“common stock”), of Entrada Therapeutics, Inc. (the “Registrant”), which become issuable under the Entrada Therapeutics, Inc. 2021 Stock Option and Incentive Plan (the “2021 Plan”) or the Entrada Therapeutics, Inc. 2021 Employee Stock Purchase Plan (the “2021 ESPP”) by reason of any stock dividend, stock split, recapitalization or any other similar transaction effected without the receipt of consideration which results in an increase in the number of outstanding shares of common stock. Pursuant to Rule 416(c) under the Securities Act, this Registration Statement shall also cover an indeterminate amount of interests to be offered or sold pursuant to the employee benefit plans described herein.
(2) Represents an automatic increase of 1,338,081 shares of common stock to the number of shares available for issuance under the 2021 Plan, effective as of January 1, 2024. Shares available for issuance under the 2021 Plan were previously registered on registration statements on Form S-8 (File No. 333-260563, File No. 333-263556 and File No. 333-270286) filed with the Securities and Exchange Commission (the “SEC”) on October 28, 2021, March 15, 2022 and March 6, 2023, respectively.
(3) Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(c) and (h)(1) of the Securities Act, and based on $12.39, the average of the high and low sale prices of common stock as reported on the Nasdaq Global Market on March 6, 2024.
(4) Represents an automatic increase of 334,520 shares of common stock to the number of shares available for issuance under the 2021 ESPP, effective as of January 1, 2024. Shares available for issuance under the 2021 ESPP were previously registered on registration statements on Form S-8 (File No. 333-260563, File No. 333-263556 and File No. 333-270286) filed with the SEC on October 28, 2021, March 15, 2022 and March 6, 2023, respectively.
(5) Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(c) and (h)(1) of the Securities Act, and based on 85% of $12.39, the average of the high and low sale prices of common stock as reported on the Nasdaq Global Market on March 6, 2024. Pursuant to the 2021 ESPP, the purchase price of the shares of common stock reserved for issuance thereunder will be 85% of the fair market value of a share of common stock on the first trading day of the applicable offering period or on the exercise date of the applicable offering period, whichever is less.